Charles J. Smith
Assistant Professor
Office Address: Department of Radiology, Universityof Missouri-Columbia
Mailing Address: Radiopharmaceutical Sciences Institute, Room A005, 800 Hospital Drive , Harry S. Truman Memorial Veterans' Hospital, Columbia MO 65201
Phone: (573) 814-6000, ext. 3683
Fax: (573) 882-1663
Email: SmithCJ@missouri.edu

Education:
  Ph.D. Chemistry, University of Missouri-Columbia
  B.S. Chemistry, Southwest Missouri State University

Professional Experience:

2004-present Assistant Professor, Department of Radiology, University of Missouri-Columbia School of Medicine
2004-present Research Assistant Professor, Missouri University Research Reactor, Columbia, MO 65211
2003-present Research Scientist WOC Appointment, Harry S. Truman Memorial Veterans Hospital, Columbia, MO 65201
2003-2004 Research Assistant Professor, Department of Internal Medicine, University of Missouri-Columbia
2002-present Adjunct Assistant Professor, Nuclear Science and Engineering Institute, University of Missouri-Columbia
2002-present Consultant to the International Atomic Energy Agency
2000-2003 Senior Research Chemist, University of Missouri-Columbia School of Medicine and the Radiopharmaceutical Sciences Institute,
2000-present Research Chemist WOC Appointment, United States Department of Veterans Affairs, Harry S. Truman Memorial Veterans Hospital,
1998-2000 Research Chemist, University of Missouri-Columbia , Radiopharmaceuticals Research Program, University of Missouri-Columbia Research Reactor Facility,
1997-1998 Post Doctoral Fellow/Research Chemist, University of Missouri-Columbia School of Medicine Department of Radiology,
1995-1997 Research Assistant, University of Missouri-Columbia Center for Radiological Research,
1992-1994 Teaching and Research Assistant, Universityof Missouri-Columbia

 
Recent Publications:
  1. Miller, W. H.; Hartmann-Siantar, C.; Descalle, M.A.; Lehmann, J.; Lewis, M.R.; Hoffman, T.J.; Smith, C.J.; Situ, P. and Volkert, W.A. Mouse Organ Absorbed Dose Fractions for Beta Emitters,Trans. Am. Nucl. Soc., 2003, 89, 689-692.
  2. Smith, C.J.; Volkert, W.A.; and Hoffman, T.J. Gastrin Releasing Peptide (GRP) Receptor-Targeted Radiopharmaceuticals: A Concise Update. (Nucl. Med. Biol., 2003, 30, 861-868).
  3. Ketring, A.R.; Ehrhardt, G.J.; Embree, M.F.; Bailey, K.D.; Tyler, T.T.; Gawenis, J.A.; Jurisson, S.S.; Engelbrecht, H.P.; Smith, C.J.; and Cutler, C.S. Production and Supply of High Specific Activity Radioisotopes for Radiotherapy Applications.Alasbimn Journal, 2003, 5 (19), 1-7.
  4. Smith , C.J. ; Sieckman, G.L.; Owen, N.K.; Hayes, D.L.; Mazuru, D.L.; Volkert, W.A.; and Hoffman, T.J. Radiochemical Investigations of [ 188 Re(H 2 O)(CO) 3 -Dpr-SSS-Bombesin(7-14)NH 2 ]: Syntheses, Radiolabeling, and In Vitro / In Vivo Studies Where Dpr = Diaminopropionic Acid. Anticancer Research, 2003, 23 (2), 63-70.
  5. Hoffman, T.J.; Gali, H.; Smith, C.J. ; Sieckman, G.L.; Hayes, D.L.; Owen, N.K.; and Volkert, W.A.; Novel Series of Indium-111 Labeled Bombesin Analogues as Potential Radiopharmaceuticals for Specific Targeting of Gastrin Releasing Peptide (GRP) Receptors Expressed on Human Prostate Cancer Cells. J. Nucl. Med., 2003, 44, 823-831.
  6. Smith, C.J. ; Sieckman, G.L.; Owen, N.K.; Hayes, D.L.; Mazuru, D.G.; Kannan, R.; Volkert, W.A.; and Hoffman, T.J. Radiochemical Investigations of GRP Receptor-specific [ 99m Tc(X)(CO) 3 - Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH 2 )] in PC-3, Tumor-bearing, Rodent Models: Syntheses, Radiolabeling, and In Vitro / In Vivo Studies Where Dpr = 2,3-Diaminopropionic acid and X = H 2 O or P(CH 2 OH) 3. Cancer Research, 2003, 63, 4082-4088.
  7. Smith, C.J. ; Gali, H.; Sieckman, G.L.; Hayes, D.L.; Owen, N.K.; Mazuru, D.G.; Volkert, W.A.; Hoffman, T.J. Radiochemical Investigations of 177 Lu-DOTA-8-BBN[7-14]NH 2 : An In Vitro / In Vivo Assessment of the Targeting Ability of this New Radiopharmaceutical for PC-3 Human Prostate Cancer Cells. Nucl. Med. Biol., 2003, 30 (3), 101-109.
  8. Smith, C.J.; Gali, H.; Sieckman, G.L.; Higginbotham, C.; Volkert, W.A.; Hoffman, T.J. Radiochemical Investigations of 99m Tc-N 3 S-X-BBN(7-14)NH 2: An In Vitro/In Vivo Structure-Activity Relationship Study Where X = 0, 3, 5, 8, and 11-Carbon Tethering Moieties. Bioconjugate Chem., 2003, 14, 93-102.
  9. Li, W.P.; Smith, C.J.; Cutler, C.S.; Ketring, A.R; Jurisson, S.S. Aminocarboxylate and Octreotide Complexes with No Carrier Added 177 Lu, 166 Ho, and 149 Pm. Nucl. Med. Biol., 2003, 30, 241-251.
  10. Smith , C.J. ; Sieckman, G.L.; Owen, N.K.; Hayes, D.L.; Mazuru, D.L.; Kannan, R.; Volkert, W.A.; and Hoffman, T.J. Radiochemical Investigations of [99m Tc(H 2 O)(CO)3 -Dpr-(X)-Bombesin(7-14)NH 2], a New Family of GRP-receptor Targeting Radiopharmaceuticals. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine. M. Nicolini, U. Mazzi Eds., SGE Editoriali, Padova, Italy. Volume 6, 2002, 339.
  11. Smith, C.J.; Hoffman, T.J.; Gali, H.; Hayes, D.L.; Owen, N.K.; Sieckman, G.L.; Volkert, W.A. Detailed Radiochemical Investigations of 177 Lu-DOTA-8-Aoc-BBN[7-14]NH 2 : A New Gastrin Releasing Peptide Receptor (GRPr) Targeting Radiopharmaceutical. J. Labeled Compd. Radiopharm., 2001, 44 (1), S706.
  12. Cutler, C.S.; Smith, C.J.; Ehrhardt, G.J.; Tyler, T.T.; Jurisson, S.S.;. Deutsch, E. Current and Potential Therapeutic Uses of Lanthanide Radioisotopes. Cancer Biotherapy & Radiopharmaceuticals, 2000, 15(6), 531.

 

Copyright © 2006 — Curators of the University of Missouri.
All rights reserved. DMCA and other copyright information.
An equal opportunity/affirmative action institution.
Please send all questions and comments to the Webmaster
Last updated on 5/9/04