RAGHURAMAN KANNAN

Research Assistant Professor
Office Address: 301 Business Loop 70 West/Room 106
Department of Radiology
University of Missouri-Columbia
Columbia , MO 65211
Phone: (573) 882-5676
Fax: (573) 884-5679
Email: KannanR@health.missouri.edu

Education:
1999 Ph.D Chemistry, Indian Institute of Science, Banglore
1993 M.S Chemistry, Indian Institute of Technology, Chennai

Professional Experience:
2000- 2002 Post-Doctoral Fellow, Department of Radiology/Chemistry, University of Missouri-Columbia, Columbia , MO

Research Interests:
•  Application of Nanoparticles in the field of medicine
•  Design and development of novel bifunctional chelate agents and their transition metal complexes, and investigate their applications for both catalysis and biomedicine.
•  Chemical and biomedical aspects of non-linear optical materials.
•  Development of new generation of chemotherapeutic agents.
•  Organometallic chemistry of specific transition metals with new chiral bisphosphanes and functionalized phosphanes-synthetic and catalytic aspects.
•  Structures of Water and Water-Methanol Clusters
Recent Publications:
  1. Characterization of Supramolecular (H 2 O) 18 Water Morphology and Water-Methanol (H 2 O) 15 (CH 3 OH) 3 Clusters in a Novel Phosphorus Functionalized Trimeric Amino Acid Host, K. Raghuraman , Kavita K. Katti, Leonard J. Barbour, Nagavarakishore Pillarsetty, Charles L. Barnes, and Kattesh V. Katti, J. Am. Chem. Soc. 2003, 125 , 6955-6961.
  2. Radiochemical Investigations of Gastrin-releasing Peptide Receptor-specific [ 99m Tc(X)(CO) 3 -Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH 2 )] in PC-3, Tumor-bearing, Rodent Models: Syntheses, Radiolabeling, and in Vitro/in Vivo Studies where Dpr = 2,3-Diaminopropionic acid and X = H 2 O or P(CH 2 OH) 3 . Smith, C. Jeffrey; Sieckman, Gary L.; Owen, Nellie K.; Hayes, Donald L.; Mazuru, Dana G.; Kannan, Raghuraman ; Volkert, Wynn A.; Hoffman, Timothy J. Cancer Research 2003, 63 , 4082-4088.
  3. Syntheses, in vitro and in vivo characterization of a 99m Tc(I)-tricarbonyl-benzylamino-dihydroxymethayl phosphine (NP 2 ) chelate, K. K. Kothari, K. Raghuraman , N. K. Pillarsetty, T. J. Hoffman, N. K. Owen, K. V. Katti, W. A. Volkert, Applied Radiation and Isotopes 2003, 58 , 543-549.
  4. Exceptional Kinetic Propensity of Hydroxymethyl Phosphanes Toward Rh(III) Stabilization in Water, K. Raghuraman , N. Pillarsetty, W. A. Volkert, C. Barnes, S. Jurisson and K. V. Katti, J. Am. Chem. Soc. 2002, 124 , 7276-7277.
  5. First Examples of Azaphosphanes as Efficient Electron Donors in the Chemical Architecture of Thermally Stable New Nonlinear Optical Materials, K. V. Katti, K. Raghuraman , N. Pillarsetty, S. R. Karra, R. J. Gulotty, M. A. Chartier, and C. A. Langhoff, Chemistry of Materials 2002, 14 , 2436-2438
  6. Novel Tridentate Water-Soluble Phosphane Based Ligands for Stabilizing Tc(I)/Re(I) Carbonyls for Radiopharmaceutical Applications, K.V. Katti, K. Raghuraman , N. Pillarsetty, W.A. Volkert, S.S. Jurisson and T.J. Hoffman Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine .   M. Nicolini, U. Mazzi Eds., SGE Editoriali, Padova , Italy . 2002, 6 , 69.
  7. Novel Green Chemistry in the Phosphonate Assisted Catalytic Hydrogenation of Olefins, K. Raghuraman , N. Pillarsetty, K. R. Prabhu, K. V. Katti, Phosphorus Sulfur and Silicon, 2002, 177 , 1951.
  8. Half-sandwich Cyclopentadienyl Ruthenium Complexes of Achiral and Chiral Diphosphazanes, K. Raghuraman , S. S. Krishnamurthy and M. Nethaji, J. Chem. Soc., Dalton . Trans., 2002, 22 , 4289-4295.
  9. New Phosphorus Chemistry Leads to Unnatural Aminoacid Trimers, K. V. Katti, K. Raghuraman , K. K. Katti, N. Pillarsetty, and C. L. Barnes, Phosphorus Sulfur and Silicon, 2002, 127 , 1587-1589
  10. Synthesis and Characterization of Ru(0), Rh(I), Pd(II) and Pt(II) Complexes Derived from Diphosphazane Monosulfide Ligands: X-ray Crystal Structures of [Ru 3 (m 3-S)(m sb -CO)(CO) 7 {h 2 -(Ph 2 PN(( S )-*CHMePh)PPh 2 )}] and [Rh(CO)Cl {h 2-(Ph ­2 ­PN((S)-*CHMePh)P(S)Ph­2­)}], K. Raghuraman, S. S. Krishnamurthy and M. Nethaji, J.Organometallic Chem., 2003, 669, 79-86.
  11. Organometallic chemistry of Diphosphazane ligands: Synthesis and structural characterization: K. Raghuraman , Swadhin K Mandal, T S Venkatakrishnan, Setharampattu S Krishnamurthy and Munirathinam Nethaji". Proc. Ind. Acad of Sci. (Chem Sci.,) 2002, 114 , 233-246.
  12. Radiochemical Investigations of [99m Tc(H 2 O)(CO) 3 -Dpr-(X)-Bombesin(7-14)NH 2], a New Family of GRP-receptor Targeting Radiopharmaceuticals. Smith, C.J.; Sieckman, G.L.; Owen, N.K.; Hayes, D.L.; Mazuru, D.L.; Kannan, R .; Volkert, W.A.; and Hoffman, T.J.  Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine . M. Nicolini, U. Mazzi Eds., SGE Editoriali, Padova, Italy . 2002, 6, 339.

 

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